With Git LFS enabled, you'll be able to fetch, modify, and push large files just as you would expect with any file that Git manages. However, a user that doesn't have Git LFS will experience a different workflow.
Git Large File Storage on GitHub Enterprise is part of an early access technical preview. It is not currently supported for production use. If you experience any issues, contact GitHub Enterprise support.
If collaborators on your repository don't have Git LFS installed, they won't have access to the original large file. If they attempt to clone your repository, they will only fetch the pointer files, and won't have access to any of the actual data.
Tip: To help users without Git LFS enabled, we recommend you set guidelines for repository contributors that describe how to work with large files. For example, you may ask contributors not to modify large files, or to upload changes to a file sharing service like Dropbox or Google Drive.
Viewing large files in pull requests
GitHub Enterprise can show any text file within a pull request, as well as several non-text files.
For files that GitHub Enterprise can't render, only the pointer file is shown:
In order to view changes made to these large files, check out the pull request locally to review the diff.